I-hormone yesitshalo i-abscisic acid (ABA) iyisilawuli esibalulekile ekuzivumelaniseni nezitshalo ze-abiotic stress.Ukulawulwa kwe-co-receptor PP2C amaprotheni afana ne-ABI1 iyihabhu emaphakathi yokudluliselwa kwesignali ye-ABA.Ngaphansi kwezimo ezijwayelekile, i-ABI1 ibophezela ku-protein kinase SnRK2s futhi ivimbele umsebenzi wayo.I-ABA eboshelwe kuphrotheni yesamukeli i-PYR1/PYLs iqhudelana nama-SnRK2s ekuqondiseni i-ABI1, ngaleyo ndlela ikhiphe ama-SnRK2 futhi ivule impendulo ye-ABA.
Ithimba labacwaningi eliholwa uSolwazi Xie Qi ovela ku-Institute of Genetics and Developmental Biology ye-Chinese Academy of Sciences kade lafunda ukutholakala kwendawo yonke, indlela yokuguqula ngemva kokuhumusha elawula ukusayinda kwe-ABA.Umsebenzi wabo wangaphambilini wembula i-endocytosis ye-PYL4 elamulwa ukutholakala kwendawo yonke ye-E2-like protein VPS23, futhi i-ABA ikhuthaza i-XBAT35 ukuthi ilulaze i-VPS23A, ngaleyo ndlela ikhulule umphumela wokuvimbela ku-ABA receptor PYL4.Kodwa-ke, ukuthi ukusayinda kwe-ABA kuhilela amaprotheni athile e-E2 adingekayo ukuze kutholakale yonke indawo, nokuthi ukusayinda kwe-ABA kulawula kanjani ukugcwala akukaqondwa ngokugcwele.
Muva nje, bahlonze i-enzyme ethize ye-E2 UBC27, elawula kahle ukubekezelela isomiso kanye nokusabela kwe-ABA ezitshalweni.Ngokuhlaziywa kwe-IP/MS, banqume ukuthi i-ABA co-receptor ABI1 kanye ne-RING-type E3 ligase AIRP3 zingamaprotheni asebenzisanayo we-UBC27.
Bathole ukuthi i-UBC27 isebenzisana ne-ABI1 futhi ithuthukisa ukuwohloka kwayo, futhi ivule umsebenzi we-E3 we-AIRP3.I-AIRP3 isebenza njenge-E3 ligase ye-ABI1.
Ngaphezu kwalokho, i-ABI1 isebenzisa i-epistasis ye-UBC27 ne-AIRP3, kuyilapho umsebenzi we-AIRP3 uncike ku-UBC27.Ngaphezu kwalokho, ukwelashwa kwe-ABA kudala ukuvezwa kwe-UBC27, kuvimbela ukucekelwa phansi kwe-UBC27, futhi kuthuthukisa ukusebenzisana phakathi kwe-UBC27 ne-ABI1.
Le miphumela yembula inkimbinkimbi entsha ye-E2-E3 ekonakalisweni kwe-ABI1 kanye nokulawulwa okubalulekile nokuyinkimbinkimbi kokusayinwa kwe-ABA ngohlelo lwe-ubiquitination.
Isihloko sephepha sithi “UBC27-AIRP3 ubiquitination complex ilawula ukusayina kwe-ABA ngokuphromotha ukucekelwa phansi kwe-ABI1 e-Arabidopsis thaliana.”Ishicilelwe ku-inthanethi ku-PNAS ngo-Okthoba 19, 2020.
Ungaqiniseka ukuthi abasebenzi bethu abahleli bazoqapha ngokucophelela yonke impendulo ethunyelwayo futhi bazothatha izinyathelo ezifanele.Umbono wakho ubaluleke kakhulu kithi.
Ikheli lakho le-imeyili lisetshenziselwa ukwazisa umamukeli kuphela othumele i-imeyili.Ikheli lakho noma ikheli lomamukeli ngeke lisetshenziselwe enye injongo.Ulwazi olufakayo luzovela ku-imeyili yakho, kodwa i-Phys.org ngeke ilugcine lunoma yiluphi uhlobo.
Thumela izibuyekezo zamasonto onke kanye/noma zansuku zonke ebhokisini lakho lokungenayo.Ungazikhipha ohlwini noma nini, futhi ngeke sabelane ngemininingwane yakho nabantu besithathu.
Le webhusayithi isebenzisa amakhukhi ukusiza ukuzulazula, ukuhlaziya ukusebenzisa kwakho amasevisi ethu futhi inikeze okuqukethwe okuvela kwabanye abantu.Ngokusebenzisa iwebhusayithi yethu, uyaqinisekisa ukuthi ufundile futhi waqonda inqubomgomo yethu yobumfihlo kanye nemibandela yokusebenzisa.