Bo-rasaense ba senola mokhoa o mocha oa taolo oa E2-E3 e rarahaneng ea UBC27-AIRP3 ho abscisic acid co-receptor ABI1.

Hormone ea semela abscisic acid (ABA) ke molaoli oa bohlokoa oa ho ikamahanya le khatello ea kelello ea limela.Taolo ea protheine ea co-receptor PP2C joalo ka ABI1 ke setsi se bohareng sa phetisetso ea lets'oao la ABA.Tlas'a maemo a tloaelehileng, ABI1 e tlama ho protein kinase SnRK2s mme e thibela tšebetso ea eona.ABA e tlameletsoe ho protheine ea receptor PYR1/PYLs e qothisana lehlokoa le SnRK2s ho lebisa tlhokomelo ho ABI1, kahoo e lokolla SnRK2s le ho kenya tšebetsong karabo ea ABA.
Sehlopha sa lipatlisiso se etelletsoeng pele ke Moprofesa Xie Qi ho tsoa Setsing sa Liphatsa tsa lefutso le Biology ea Tsoelo-pele ea Setsi sa Setsi sa Mahlale sa China se 'nile sa ithuta ka hohle-hohle, mokhoa oa ho fetola ka morao ho phetolelo o laolang pontšo ea ABA.Mosebetsi oa bona o fetileng o ile oa senola endocytosis ea PYL4 e kentsoeng ke ho ata ha protheine ea E2-joaloka VPS23, 'me ABA e khothalletsa XBAT35 ho senya VPS23A, kahoo e lokolla phello ea inhibitory ho ABA receptor PYL4.Leha ho le joalo, hore na pontšo ea ABA e kenyelletsa liprotheine tse khethehileng tsa E2 tse hlokahalang bakeng sa ho fumaneha hohle, le hore na pontšo ea ABA e laolang hohle hohle ha e e-s'o utloisisehe ka botlalo.
Haufinyane tjena, ba khethile enzyme e itseng ea E2 UBC27, e laolang mamello ea komello le karabelo ea ABA limela.Ka tlhahlobo ea IP/MS, ba fumane hore ABA co-receptor ABI1 le RING-type E3 ligase AIRP3 ke liprotheine tse sebelisanang tsa UBC27.
Ba fumane hore UBC27 e sebelisana le ABI1 mme e khothalletsa ho senyeha ha eona, le ho kenya tšebetsong tšebetso ea E3 ea AIRP3.AIRP3 e sebetsa joalo ka E3 ligase ea ABI1.
Ho feta moo, ABI1 e fana ka epistasis ea UBC27 le AIRP3, ha mosebetsi oa AIRP3 o itšetlehile ka UBC27.Ntle le moo, kalafo ea ABA e susumetsa polelo ea UBC27, e thibela ho senyeha ha UBC27, hape e ntlafatsa tšebelisano lipakeng tsa UBC27 le ABI1.
Liphetho tsena li senola mokhoa o mocha oa E2-E3 ho senyeha ha ABI1 le taolo ea bohlokoa le e rarahaneng ea pontšo ea ABA ka tsamaiso ea hohle.
Sehlooho sa pampiri ke "UBC27-AIRP3 ubiquitination complex e laola pontšo ea ABA ka ho khothalletsa ho senyeha ha ABI1 ho Arabidopsis thaliana."E phatlalalitsoe marang-rang ho PNAS ka la 19 Mphalane 2020.
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Nako ea poso: Dec-07-2020