Cov nroj tsuag hormone abscisic acid (ABA) yog ib qho tseem ceeb regulator nyob rau hauv cov nroj tsuag abiotic stress adaptation.Kev tswj ntawm co-receptor PP2C protein zoo li ABI1 yog lub hauv paus hub ntawm ABA teeb liab hloov.Raws li cov txheej txheem, ABI1 khi rau cov protein kinase SnRK2s thiab inhibits nws cov haujlwm.ABA khi rau receptor protein PYR1 / PYLs sib tw nrog SnRK2s hauv kev tsom ABI1, yog li tso tawm SnRK2s thiab ua kom cov lus teb ABA.
Pab neeg tshawb fawb coj los ntawm xibfwb Xie Qi los ntawm lub koom haum ntawm Genetics thiab Developmental Biology ntawm Suav Academy ntawm Sciences tau ntev tau kawm txog ubiquitination, ib qho kev hloov kho tom qab kev txhais lus uas tswj ABA signaling.Lawv txoj haujlwm yav dhau los tau qhia txog qhov endocytosis ntawm PYL4 kho los ntawm ubiquitination ntawm E2-zoo li protein VPS23, thiab ABA txhawb nqa XBAT35 kom degrade VPS23A, yog li tso tawm cov nyhuv inhibitory ntawm ABA receptor PYL4.Txawm li cas los xij, seb ABA signaling cuam tshuam nrog cov E2 cov proteins uas yuav tsum tau muaj rau ubiquitination, thiab yuav ua li cas ABA signaling tswj ubiquitination tseem tsis tau to taub tag nrho.
Tsis ntev los no, lawv tau txheeb xyuas qhov tshwj xeeb E2 enzyme UBC27, uas tswj tau qhov zoo ntawm drought kam rau ua thiab ABA teb hauv cov nroj tsuag.Los ntawm kev txheeb xyuas IP / MS, lawv tau txiav txim siab tias ABA co-receptor ABI1 thiab RING-type E3 ligase AIRP3 yog cov protein sib cuam tshuam ntawm UBC27.
Lawv pom tias UBC27 cuam tshuam nrog ABI1 thiab txhawb nqa nws qhov kev puas tsuaj, thiab ua rau E3 kev ua haujlwm ntawm AIRP3.AIRP3 ua raws li E3 ligase ntawm ABI1.
Tsis tas li ntawd, ABI1 exerts lub epistasis ntawm UBC27 thiab AIRP3, thaum lub luag haujlwm ntawm AIRP3 yog UBC27-dependent.Tsis tas li ntawd, kev kho ABA induces qhov kev qhia ntawm UBC27, inhibits qhov degradation ntawm UBC27, thiab txhim khu kev sib cuam tshuam ntawm UBC27 thiab ABI1.
Cov txiaj ntsig no nthuav tawm qhov tshiab E2-E3 txoj hauv kev degradation ntawm ABI1 thiab txoj cai tseem ceeb thiab nyuaj ntawm ABA signaling los ntawm ubiquitination system.
Lub npe ntawm daim ntawv yog "UBC27-AIRP3 ubiquitination complex tswj ABA signaling los ntawm kev txhawb kev degradation ntawm ABI1 hauv Arabidopsis thaliana."Nws tau tshaj tawm online ntawm PNAS thaum Lub Kaum Hli 19, 2020.
Koj tuaj yeem tso siab tau tias peb cov neeg ua haujlwm kho mob yuav saib xyuas txhua qhov kev tawm tswv yim xa mus thiab yuav ua qhov tsim nyog.Koj lub tswv yim tseem ceeb heev rau peb.
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Xa txhua lub limtiam thiab/lossis hloov tshiab txhua hnub rau koj lub inbox.Koj tuaj yeem tshem tawm txhua lub sijhawm, thiab peb yuav tsis qhia koj cov ntsiab lus rau peb tog.
Lub vev xaib no siv cov ncuav qab zib los pab kev taw qhia, txheeb xyuas koj qhov kev siv peb cov kev pabcuam thiab muab cov ntsiab lus los ntawm peb tog.Los ntawm kev siv peb lub vev xaib, koj paub tseeb tias koj tau nyeem thiab nkag siab txog peb txoj cai ntiag tug thiab cov ntsiab lus ntawm kev siv.